By S. B. Field (auth.), Dr. med. Dipl. biochem. Rolf D. Issels, Prof. Dr. med. Wolfgang Wilmanns (eds.)

Physicians, biologists and physicists current their contemporary paintings within the box of hyperthermia with reference to either its software and its mix with radiation and chemotherapy. present technical probabilities, medical administration and significant points of its use for superficial and deep-seated tumors are mentioned. the most issues mentioned are: alterations of metabolism and microcirculation below warmth stipulations, the organic interplay of warmth with X-rays and a number of other chemotherapeutic brokers, and the latest scientific info from varied associations at the mixed program within the remedy of cancer.

Show description

Read Online or Download Application of Hyperthermia in the Treatment of Cancer PDF

Similar cancer books

Cancer Neutron Capture Therapy

There are various human cancers which actively synthesize particular attribute proteins corresponding to melanomas, thyroid melanoma and squamous cellphone carcinoma. Many melanoma researchers have in fact attempted to make use of this particular task as a key for the selective remedy of cancers. some time past for instance, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was once synthesized as Melphalan and used to regard malignant cancer.

Testicular Cancer and Other Tumors of the Genitourinary Tract

The complaints of this quantity characterize a list of a gathering within the Ettore Majorana heart in Erice, Sicily from 16-24 July, 1983. This used to be the 5th process the foreign tuition of Urology and Nephrology, the fourth in a sequence of conferences dedicated to diversified elements of Urological Oncology.

Additional info for Application of Hyperthermia in the Treatment of Cancer

Sample text

1986). It is therefore likely that during hyperthermic treatment the pH of the tumour tissue decreases, although human data on this subject are lacking. There is, however, evidence that human tumour pH is lower than normal tissue pH. For reviews, see Thistlethwaite et al. (1985) and Wike-Hooley et al. (1984). The only data on human tumour pH during hyperthermia were obtained during whole-body hyperthermia (Van der Zee et al. 1983) and did not show a change in pH. Another point which is not yet explained is that during hyperthermic treatment there is a slight increase in tumour volume.

1985) and Wike-Hooley et al. (1984). The only data on human tumour pH during hyperthermia were obtained during whole-body hyperthermia (Van der Zee et al. 1983) and did not show a change in pH. Another point which is not yet explained is that during hyperthermic treatment there is a slight increase in tumour volume. An example of this is shown in Fig. 7. No explanation for this phenomenon has yet been offered, although several authors, including Vaupel et al. (1983) report the development of oedema in the tumour interstitium during hyperthermic treatment.

U-- _ ~\ D M CLI(IJ ....... :::::J::J VJu) , ,, , , ,f M CLlCU VI ....... ::J::::J U') ~ QlCU VIII) ...... ::::J:::I ::::J:J 00000000 ~~~~ to t, 12 13 Fig. 2. Plasma acetate levels in seven tumor patients with small cell carcinoma of the lung at the first and the third course of thennochemotherapy. In six patients acetate levels decreased from the first to the third course. These patients showed a partial remission. In one patient acetate levels increased. Neumann et al. - a. ----1/------. - - 11- 50 Hyperthermia t, Fig.

Download PDF sample

Rated 4.83 of 5 – based on 19 votes