By W. R. Lee MD, FRCPath, FCOphth, FRSE (auth.)

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If the uveitis does not abate within a two to three week period, many ophthalmologists will enucleate a traumatised eye in which vision is poor or absent, in order to avoid the risk of sympathetic ophthalmitis (see p. 39). The orientation of tissue blocks taken from the enucleated eye is again governed by the need to obtain sections through the regions of interest. Reparative Changes in Ocular Tissues Traumatised eyes enucleated at periods between two and three weeks after trauma will in most cases show a pattern of repair in which granulation tissue formation is prominent in the region of the perforating wound.

Arch Ophthalmol 64:904 Marcus OM, Minkovitz JB, Wardwell SO, Albert OM (1990) The value of nucleolar organizer regions in uveal melanoma. Am J Ophthalmol110:527-534 Margo CE (1986) Special histochemical stains in ocular pathology. Surv Ophthalmol31:131- 135 Olver JM, McCartney ACE (1989) Anterior segment vascular casting. Eye 3:303-307 Petrash JM (1992) Application of molecular biological techniques to the understanding of visual system disorders. Am J Ophthalmol 113:573- 581 Polak JM, van Noorden S (1983) Immunocytochemistry .

5 em). 6. An even illumination system. It should be stressed that a globe must be photographed as soon as the primary cuts are made. If the specimen lies in a fluid which contains debris, the vitreous quickly becomes contaminated and the photographic result is spoilt. Ophthalmic Histopathology 18 Many of the illustrations prepared for this book were made on a simple slide copying device which was considered to be obsolete for its original purpose. The essential feature for good depth of focus is to stop down to f32 and to take exposures for the necessary time interval- which can be up to 2 minutes but is usually in the range of 5-20 seconds.

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