By Miles J. Padgett, Justin Molloy, David McGloin
The technical improvement of optical tweezers, besides their program within the organic and actual sciences, has advanced considerably because the demonstration of an optical catch for micron-sized debris according to a unmarried, tightly targeted laser beam used to be first mentioned greater than 20 years in the past. Bringing jointly many landmark papers at the box, Optical Tweezers: equipment and Applications covers the suggestions and makes use of of optical tweezers.
Each part is brought by means of a quick statement, atmosphere the papers into their historic and modern contexts. the 1st sections discover the pioneering paintings of Arthur Ashkin and using optical tweezers in organic structures. The booklet then discusses the wide use of optical tweezers for the size of picoNewton forces and examines a number of techniques for modeling forces inside of optical tweezers. the following elements clarify how optical tweezers are utilized in colloid technology, easy methods to convert optical tweezers into optical spanners, and the way spatial mild modulators create holographic tweezers. The ebook concludes with a bit on rising functions of optical tweezers in microfluidic systems.
With contributions from the superior within the box, this compendium provides vital historic and present advancements of optical tweezers in quite a number clinical components, from the manipulation of micro organism to the therapy of DNA.
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Additional info for Optical tweezers : methods and applications
In most of our experiments with silica colloids or TMV in water, we noticed the appearance of some strange new particles in diluted samples that had been kept around for several days. They were quite large com pared to Rayleigh particles, on the basis of their scattering of light, and were apparently self-propelled. They were clearly observed moving through the distribution of smaller slowly diffusing Rayleigh-sized colloidal particles at speeds as high as hundreds of micrometers per second. They could stop, start up again, and frequendy reversed their direction of motion at the boundaries of the 33 power auxiliary red laser beam directed trans verse to the trap axis.
P. Gordon, R. Kompfner, and P. A. Wolff. I thank J. M. Dziedzic for making his equipment and skill available. 1 E . F . Nichols and G. F . Hull, P h y s . Rev. 17, 26, 91 (1903). 2 P . Debye, Ann. P h y s i k 30, 57 (1909). 3 N. A. F u c h s , The Mechanics of A e r o s o l s (The M a c m i l l a n Company, New York, 1964). 4 F . Ehrenhaft and E. R e e g e r , Compt. Rend 232, 1922 (1951). 5 A. D. May, E. G. Rawson, and E. H. H a r a , J Appl. P h y s . 38, 5290 (1967); E. G. Rawson and E. H. May, Appl.
J. Tomlinson, Opt. Lett. 6, 284 (1981); and A. Ashkin, J. M. Dziedzic, and P. W Smith, Opt. Lett. 7, 276 (1982). 7. A. Ashkin, Phys. Rev. Lett. 24,146 (1970). 8. G. Roosen, Can. J. Phys. 57,1260 (1979). 9. See, for example, M. Kerker, The Scattering of Light (Academic, New York, 1969), p. 37. 10. W. Heller, J. Chem. Phys. 42,1609 (1965). 11. Nalco Chemical Company, Chicago, Illinois; Ludox col loidal silica by DuPont Corporation, Wilmington, Dela ware. 6) 31 size range of 105, from ~10 um down to a few angstroms, which includes both Mieand Rayleigh-size particles.