By H Lutz

Ultrafiltration for Bioprocessing is vital analyzing for all these excited about the biotechnology and biopharmaceutical parts. Written by means of a number one employee within the region, it comprises many useful functions and case reviews within the key strategy of ultrafiltration (UF), that is utilized in virtually each bioprocess.

  • Focuses on ultrafiltration for biopharmaceuticals—other books examine basic ultrafiltration or normal biopharmaceuticals
  • A mixture of thought and sensible applications—other books are usually extra theory-oriented
  • Addresses the most matters encountered in improvement and scale-up via techniques and case studies

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Extra resources for Ultrafiltration for Bioprocessing

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These characteristics suggest that feed stocks in the polarized region of the flux curve are best run through the lumen and feed stocks in the linear region of the flux curve are best run through the shell. A feed pump provides the cross-flow and a valve on the retentate provides back pressure. The permeate is generally kept at atmospheric pressure. The TMP and tangential flow rate decreases along the length of the fibres. 2 Hollow fibre modules: (a) module and (b) flow pattern. ) Modules 33 to characterize its operation.

Englewood Cliffs, NJ: Prentice-Hall; 1991. 17. Pujar NS, Zydney AL. Pore size distribution effects on electrokinetic phenomena in semipermeable membranes. Ind Eng Chem Res 1974;33:2473. 18. Pujar NS, Zydney AL. Electrostatic effects on protein partitioning in size-exclusion chromatography and membrane ultrafiltration. J Chromatogr A 1998;796(2):229–38. 19. Deen WM, Smith FG III. Hindered diffusion of synthetic polyelectrolytes in charged microporous membranes. J Membr Sci 1982;12(2):217–37. 20.

Hollow fibre modules are a convenient plug-and-play format for small-scale operation. They do not utilize turbulence promoters in the feed channel and show poorer mass transport than spirals or cassettes. 02 High Moderate Good High 40–200 EMD Millipore 200–900 EMD Millipore, GE, Spectrum Ease-of-use, cost Scalability, low mass transfer, high pumping Dairy, desalination Low mass transfer, high pumping Bench scale preps. 500–1,000 EMD Millipore, Pall, GE, Sartorius, Novasep High mass transfer, low pumping, scalability Cost Key advantages Key disadvantages Uses Biotech.

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