By Mark Gladwin, Bill Trattler
A quick, transparent, thorough, and hugely stress-free method of scientific microbiology, brimming with mnemonics, humor, precis charts and illustrations, from AIDS to "flesh-eating bacteria" to ebola, mad cow affliction, hantavirus, anthrax, smallpox, botulism, and so on. first-class Board evaluate.
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Additional info for Clinical Microbiology Made Ridiculously Simple (3rd Edition)
Equinus are still classified as streptococci. Bacteroides fragilis). A clinical pearl is that if a Streptococcus intermedius group bacteria grows in the blood you should suspect that there is an abscess hiding in an organ and you 26 CHAPTER 4. STREPTOCOCCI Figure 4-6 Enterococcus (faecalis and faecium) ciprofloxacin, chloramphenicol, and doxycycline. A newer class of drugs, the pristinomycins, may also be used: dalfopristin (Synercid) + quinupristin (RP 59500). These cause painful arthralgias in 2% and venous irritation (less with a central line) in 5%.
As this anaerobic organism grows, it releases its battery of exotoxin enzymes (see Fig. 2-8), causing further tissue destruction. Clinically, there are 2 classes of infection with Clostridium perfringens: 1) Cellulitis/wound infection: Necrotic skin is exposed to Clostridium perfringens, which grows and damages local tissue. Palpation reveals a moist, spongy, crackling consistency to the skin due to pockets of gas; this is called crepitus. 2) Clostridial myonecrosis: Clostridium perfringens, inoculated with trauma into muscle, secretes exotoxins that destroy adjacent muscle.
Eskola J, Kilpi T, et. al. Efficacy of a pneumococcal conjugate vaccine against otitis media. N Engl J Med 2001; 344:403-409. Holm SE, Invasive group A streptococcal infections. N. Eng. J. Med. 1996; 335: 590-591. Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases; 4th edition. New York: Churchill Livingstone, 1995;1784-1865. Stevens DL. Invasive group A streptococcus infections. Clinical Infectious Diseases 1992; 14:2-13. Stevens DL, Gibbons AE, et al. The eagle effect revisited: efficacy of clindamycin, erythromycin, and penicillin in the treatment of streptococcal myositis.