Download Gene Therapy and Gene Delivery Systems by David V. Schaffer, Weichang Zhou PDF
By David V. Schaffer, Weichang Zhou
1 D.V. Schaffer, W. Zhou: Gene treatment and Gene supply structures as destiny Human Therapeutics.- 2 J. Heidel, S. Mishra, M.E. Davis: Molecular Conjugates.- three M. Manthorpe, P. Hobart, G. Hermanson, M. Ferrari, A. Geall, B. Goff, A. Rolland: Plasmid Vaccines and Therapeutics: From layout to Applications.- four S.R. Little, R. Langer: Non-Viral supply of melanoma Genetic Vaccines.- five J.C. Grieger, R.J. Samulski: Adeno-Associated Virus as a Gene remedy Vector: Vector improvement, construction and scientific Applications.- 6 J.H. Yu, D.V. Schaffer: complex concentrating on techniques for Murine Retroviral and Adeno-Associated Viral Vectors.- 7 N. Loewen, E.M. Poeschla: Lentiviral Vectors.- eight N.E. Altaras, J.G. Aunins, R.K. Evans, A. Kamen, J.O. Konz, J.J. Wolf: creation and formula of Adenovirus Vectors.-
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Sample text
Rejman J, Oberle V, Zuhorn IS, Hoekstra D (2004) Biochem J 377:159 38 J. Heidel et al. 49. Kunath K, von Harpe A, Fischer D, Kissel T (2003) J Control Release 88:159 50. Olivier V, Meisen I, Meckelein B, Hirst TR, Peter-Katalinic J, Schmidt MA, Frey A (2003) Bioconjug Chem 14:1203 51. Labat-Moleur F, Steffan AM, Brisson C, Perron H, Feugeas O, Furstenberger P, Oberling F, Brambilla E, Behr JP (1996) Gene Ther 3:1010 52. Mislick KA, Baldeschwieler JD (1996) P Natl Acad Sci USA 93:12349 53. Kopatz I, Remy JS, Behr JP (2004) J Gene Med 6:769 54.
75 77 77 78 80 81 81 81 83 83 5 Conclusions . . . . . . . . . . . . . . . . . . 83 References . . . . . . . . . . . . . . . . . . . . 84 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Abstract In the late 1980s, Vical and collaborators discovered that the injection into tissues of unformulated plasmid encoding various proteins resulted in the uptake of the plasmid by cells and expression of the encoded proteins.
83 References . . . . . . . . . . . . . . . . . . . . 84 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Abstract In the late 1980s, Vical and collaborators discovered that the injection into tissues of unformulated plasmid encoding various proteins resulted in the uptake of the plasmid by cells and expression of the encoded proteins. After this discovery, a period of technological improvements in plasmid delivery and expression and in pharmaceutical and manufacturing development was quickly followed by a plethora of human clinical trials testing the ability of injected plasmid to provide therapeutic beneļ¬ts.