By Kenneth G. Nepple M.D., Gerald L. Andriole (auth.), J. Stephen Jones (eds.)
Based at the hugely profitable first version of Prostate Biopsy: symptoms, concepts, and Complications, this new quantity provides new options that experience emerged in resolution to present questions from its viewers. Many new views and applied sciences are provided, many from the authors’ across the world well-known paintings at the subject. monstrous advancements in suggestions and problems are explored intimately. The bankruptcy authors contain a whole spectrum of experts of their respective topic components. All authors are the world over accredited because the most advantageous experts on their selected subject matters. Prostate melanoma analysis: PSA, Biopsy, and Beyond offers new information at the debatable factor of PSA screening and thresholds as indication to accomplish biopsy. place of work established transrectal saturation biopsy is roofed intimately. different issues explored comprise template guided biopsy and image-guided biopsy in addition to a very new paradigm for prevention of complications.
Prostate melanoma prognosis: PSA, Biopsy, and Beyond can be of significant price and software to all working towards urologists.
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Additional info for Prostate Cancer Diagnosis: PSA, Biopsy and Beyond
27. Carter HB, et al. Longitudinal evaluation of prostatespeciﬁc antigen levels in men with and without prostate disease. JAMA. 1992;267(16):2215–20. 28. Oesterling JE. Age-speciﬁc reference ranges for serum PSA. N Engl J Med. 1996;335(5):345–6. 29. Catalona WJ, et al. Selection of optimal prostate speciﬁc antigen cutoffs for early detection of prostate cancer: receiver operating characteristic curves. J Urol. 1994;152(6 Pt 1):2037–42. 30. Carter HB, et al. Estimation of prostatic growth using serial prostate-speciﬁc antigen measurements in men with and without prostate disease.
As we will demonstrate, the utility of PSA at the very least remains an enduring marker after primary therapy, guiding the initiation of salvage therapy and the management of metastatic prostate cancer. By reviewing the literature, we hope to show that the serum PSA era is not over as Stamey has suggested. In fact, PSA has a growing and expanding role in the total management of prostate cancer through detection, prognosis, and management. S. 1007/978-1-62703-188-2_3, © Springer Science+Business Media New York 2013 27 28 Background The introduction of serum prostate-speciﬁc antigen (PSA) as a marker for prostate cancer and its use beginning in the late 1980s has led to a dramatic increase in prostate cancer detection.
25 ng/mL. 5 ng/mL, the risk of prostate cancer was signiﬁcantly higher. The clinical implication of this study is that a single early PSA could be used to individualize later screening for prostate cancer. 6 ng/mL), annual screening could be expected to be of little clinical beneﬁt and, likewise, men with high initial PSA could be advised that they are at a signiﬁcant increased risk for developing clinically signiﬁcant prostate cancer. Risk stratifying prostate cancer screening could retain many of the beneﬁts of screening such as reducing mortality while avoiding harm of unnecessary screening and overdiagnosis.